5-Fluorouracil-induced vasospastic angina

Thyrotoxicosis-induced vasospastic angina.

[Angina related to 5-Fluorouracil].

Treatment with 5-fluorouracil is common in oncological patients. Side effects on bone marrow, skin, and mucous membranes have been reported. Cardiotoxicity, which is less predictable, can be life-threatening. Manifestations include angina, arrhythmias, infarction, heart failure and cardiogenic shock. The toxic mechanisms that might be involved have been much discussed but have not yet been clea...

Vasospastic Angina in Identical Twins

BACKGROUND The clinical conditions of various diseases, including coronary artery disease, are determined by genetics and the environment. Previous investigations noted the significance of genetic mutations and polymorphisms in cases of coronary spasm. CASE REPORT We report on monozygotic identical twins who almost simultaneously presented with vasospastic angina. The 58-year-old younger twin...

Long lasting spasticity in controlled vasospastic angina.

OBJECTIVE To evaluate changes in coronary artery spasticity in patients with vasospastic angina who had been stable for years under continuous drug treatment. METHODS Follow up coronary angiography was performed under intracoronary ergonovine provocation in 27 well controlled patients with vasospastic angina and no organic stenosis; the tests were done > 24 months after the initial coronary a...

Prognostic stratification of patients with vasospastic angina.

Prognostic Stratification of Patients With Vasospastic Angina A Comprehensive Clinical Risk Score Developed by the Japanese Coronary Spasm Association Yusuke Takagi, MD,* Jun Takahashi, MD,* Satoshi Yasuda, MD,y Satoshi Miyata, PHD,* Ryusuke Tsunoda, MD,z Yasuhiro Ogata, MD,z Atsushi Seki, MD,x Tetsuya Sumiyoshi, MD,x Motoyuki Matsui, MD,k Toshikazu Goto, MD,k Yasuhiko Tanabe, MD,{ Shozo Sueda,...